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目的 分析9例恶性综合征（neuroleptic malignant syndrome,NMS）患者的临床资料，探讨NMS的临床特征。方法 回顾性分析2014年6月—2022年12月在徐州医科大学附属医院就诊的9例NMS患者的临床资料。结果男性4例，女性5例，中位发病年龄66岁；9例患者的临床诊断分别为精神分裂症5例，帕金森病2例，多系统萎缩1例、器质性精神病1例；患者主要临床表现为精神状态差、意识改变、高热、进食困难、气促、痰多等。7例患者病情缓解好转出院，1例患者间断无创呼吸机辅助呼吸，1例患者死亡。结论 NMS与暴露于多巴胺拮抗剂或停用多巴胺激动剂有关，早期识别和正确干预是改善预后的关键。
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基本信息:
DOI：10.20256/j.cnki.zgdxbl.20250612.008
中图分类号:R749
引用信息:
[1]李可,谭伟宏,胡珍珠,等.恶性综合征9例临床分析并文献复习[J].中国典型病例大全,2025,19(02):24-27.DOI:10.20256/j.cnki.zgdxbl.20250612.008.
基金信息:
徐州市科技项目（KC23232）