中国典型病例大全

目的 探索饮食环境、饮食行为与女童性早熟的关系，为预防女童性早熟发生提供依据。方法 按1∶1对照匹配方式选取2022年1月—2023年3月怀化市妇幼保健院儿童保健科门诊确诊为性早熟的女童为病例组，选择与病例组年龄相匹配的儿保科的正常女童为对照组。采用一般信息问卷、饮食环境测评问卷、饮食行为测评问卷进行调查。结果 共纳入研究对象419例。单因素分析可见，两组儿童BMI、骨龄、零花钱、母亲初潮年龄、不健康饮食环境、饮食种类、饮食习惯及饮食行为总分比较，差异具有统计学意义（P<0.05）。Logistic回归分析可见，高BMI(OR=1.135,95%CI:1.039～1.239)为性早熟的危险因素；母亲初潮年龄晚（OR=0.779,95%CI:0.670～0.952）、进食习惯好（OR=0.932,95%CI:0.889～0.977）为性早熟的保护性因素。结论 女童性早熟可能与不好的饮食行为有一定相关性。

Objective To explore the correlation between dietary environment, dietary behaviors and precocious puberty in girls, and provide empirical basis for preventing the occurrence of precocious puberty. Methods A 1∶1 matched study case-control study was used to select girls diagnosed with precocious puberty in the outpatient department of Huaihua Maternal and Child Health Hospital January from 2022 to March 2023 as the study group, and normal girls from the Children's Health Department who matched the age of the case group as the control group. All subjects were assessed with General information questionnaire, dietary environment assessment questionnaire and dietary behavior assessment questionnaire. Results A total of 419 study subjects were included.Univariate analysis showed that there were statistically significant differences in BMI, bone age,pocket money, maternal age of menarche, unhealthy eating environment, food intake types, eating habits and total score of eating behaviors between the two groups(P<0.05). Logistic regression analysis showed that high BMI(OR=1.135,95%CI:1.039～1.239)was a risk factor for precocious puberty. Late maternal age of menarche(OR=0.779,95%CI:0.670～0.952)and good feeding habits(OR=0.932,95%CI:0.889～0.977)were the protective factors for precocious puberty. Conclusions Girls' precocious puberty may be related to poor eating behavior.